This elementary divergence while in the active web pages of NagA from these resources suggests the system for your activation with the hydrolytic h2o and substrate expected for catalysis need to differ to a big degree.

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This observation signifies that There have been a divergence while in the evolution of NagA and indicates there are elementary discrepancies inside the mechanistic specifics for substrate activation and hydrolysis. NagA from E. coli

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b may be the dissociation constant with the team that must be protonated for complete activity. The pH profiles which showed which the deprotonation of two acid ic groups plus the protonation of one basic group are necessary for max exercise had been suit to equation 5 wherever K

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